Heat exchanger, method for manufacturing the heat exchanger, and method for manufacturing heart-lung machine

ABSTRACT

A heat exchange module  12  is formed by stacking pipe groups obtained by fixing a plurality of pipes  1  with use of pipe array holding members  9   a  to  9   d . Flow path forming members  50  are arranged on pipe groups in the uppermost and lowermost layers, and walls  51  and  52  are provided so as to protrude from the outer-side pipe array holding members and the inner-side pipe array holding members. Flow path members  63  are provided between the walls  51  and  52  adjacent to each other so as to allow through holes  53  and  54  to communicate with each other. The heat exchange module  12  is housed in the housing  2 , and while rotating the housing  2 , a resin material  24  is filled into a space enclosed by the two inner-side pipe array holding members of each pipe group in the housing  2 , interstices around the pipes present between an opening  15   a  of the housing and the outer-side pipe array holding members, and interstices around the pipes present between an opening  15   b  of the housing and the outer-side pipe array holding members.

TECHNICAL FIELD

The present invention relates to a heat exchanger, particularly to aheat exchanger used in medical equipment such as a heart-lung machine, aheart-lung machine equipped with the same, a method for manufacturingthe heat exchanger, and a method for manufacturing a heart-lung machine.

BACKGROUND ART

In heart surgery that involves cardiac arrest in a patient, a heart-lungmachine is used for taking over the functions of respiration andcirculation during the cardiac arrest. Further, during the surgery, itis necessary to lower the patient's temperature and maintain the same sothat the patient's oxygen consumption should decrease. For this purpose,the heart-lung machine is equipped with a heat exchanger to control thetemperature of blood taken out of the patient.

As such a medical-use heat exchanger, a bellows-type heat exchanger, amulti-tubular heat exchanger (see Patent Document 1, for instance),etc., have been known conventionally. Among these, the multi-tubularheat exchanger has a larger area used for heat exchange as compared withthe bellows-type heat exchanger with the same device capacity, andhence, it has the advantage of a higher heat exchange ratio as comparedwith the bellows-type heat exchanger.

Here, an example of the conventional multi-tubular heat exchanger isdescribed specifically with reference to FIGS. 9A to 9C, and 10. FIGS.9A to 9C show a configuration of a conventional heat exchanger. FIGS.9A, 9B, and 9C are a top view, a side view, and a front view of thesame, respectively.

FIG. 10 is a partially cut-off perspective view illustrating the insideof a housing of the heat exchanger shown in FIGS. 9A to 9C.

As shown in FIGS. 9A to 9C, the conventional heat exchanger includes aplurality of pipes 1 through which cold/hot water flows, a housing 102for housing the pipes, and sealing members 103 a to 103 c for sealingblood flowing over surfaces of the plurality of pipes 1. Further, asshown in FIGS. 9A to 9C and 10, the plurality of pipes 1 are arranged inparallel with one another in the housing 102.

Still further, the housing 102 includes an inlet 104 for introducingblood into the housing, and a first outlet 105 for discharging blood outof the housing. The inlet 104 is an inlet of a flow path 108 of blood,while the first outlet 105 is an outlet of the flow path 108 of blood,which will be described later.

Further, as shown in FIG. 10, in the heat exchanger, there are a firstsealing member 103 a positioned on one of end sides of the plurality ofpipes 1, a second sealing member 103 b positioned on the other end sideof the pipes, and a third sealing member 103 c positioned between thefirst and second sealing members 103 a and 103 b. The first, second, andthird sealing members 103 a, 103 b, and 103 c are involved in thesealing among the pipes 1. The third sealing member 103 c is provided sothat a gap 7 is provided between the third sealing member 103 c and thefirst sealing member 103 a, as well as a gap 7 is provided between thethird sealing member 103 c and the second sealing member 103 b. Further,as shown in FIGS. 9A to 9C, the flow path 108 is formed in the thirdsealing member 103 c so that blood introduced from the inlet 104 intothe housing 2 is guided to the first outlet 105. The third sealingmember 103 c provides a sealing for blood. Further, the housing 102 isprovided with second outlets 106 in a manner such that the secondoutlets 106 communicate with the gaps 7.

Therefore, in the conventional heat exchanger shown in FIGS. 9A to 9C,in the case where, for example, blood leaks due to seal leakage of thethird sealing member 103 c, the blood having leaked is retainedtemporarily in the gaps 7, and thereafter is discharged through thesecond outlets 106 to outside the heat exchanger. In the case wherecold/hot water leaks due to seal leakage of the first sealing member 103a or the second sealing member 103 b, the cold/hot water having leakedis retained temporarily in the gap 7, and thereafter is dischargedthrough the second outlets 106 to outside the heat exchanger. As aresult, according to the heat exchanger shown in FIGS. 9A to 9C, in boththe cases where blood leaks and where cold/hot water leaks, the leakagethrough the sealing can be detected immediately, and further, theoccurrence of blood contamination can be prevented.

It should be noted that in FIGS. 9A to 9C, 114 and 115 denote injectionholes for filling a material for forming the sealing members, which areprovided on the top face of the housing 102, and 116 and 117 denote airvents used upon the filing of the material for forming the sealingmembers, which are formed on side faces of the housing 102. Theinjection holes 114 and 115, and the air vents 116 and 117 are describedlater.

Next, as to a series of principal steps of a process for manufacturingthe conventional heat exchanger shown in FIGS. 9A to 9C and 10 aredescribed below, with reference to FIGS. 11 to 14. FIGS. 11A to 11C showpipe groups composing a heat exchange module; FIGS. 11A, 11B, and 11Care a top view, a front view, and a perspective view, respectively.FIGS. 12A, 12B, and 12C are a heat exchange module composed of aplurality of pipes; FIGS. 12A to 12C are a top view, a front view, and aperspective view, respectively. FIG. 13 is a top view illustrating thestate in which the housing is attached to a jig so that sealing membersare formed. FIG. 14 is a cross-sectional view showing a step for formingthe sealing members.

First, as shown in FIGS. 11A to 11C, a pipe group 10 is formed, whichincludes two or more (nine in the example shown in FIGS. 11A to 11C)pipes 1 arrayed in a row in parallel with one another, and pipe arrayholding members 9 a to 9 d, each of which is present in gaps between thepipes and holds the array of the pipes 1. In the pipe group 10, the pipearray holding members 9 a to 9 d are in a state of being pierced by thepipes 1, whereby the array of the pipes 1 is held. The pipe arrayholding members 9 are formed in a belt-like shape, and the two or morepipes 1 are arrayed in a row in the lengthwise direction of the belt.Further, four of the pipe array holding members 9 are arranged along thecentral axes of the pipes 1.

In the example shown in FIGS. 11A to 11C, the pipe group 10 is formed bypouring a resin into a die in which the two or more pipes 1 are arrangedso that the pipe array holding members 9 a to 9 d are formed; that is,the pipe group 10 is formed by insert molding. A plurality of the pipegroups 10 are produced. Further, the pipe array holding members 9 a to 9d are provided with a plurality of recessed portions 11.

Next, as shown in FIGS. 12A to 12C, a heat exchange module 12 is formedby stacking a plurality of pipe groups 10. Here, the pipes 1 composingeach pipe group 10 are fitted in the recessed portions 11 provided atthe pipe array holding members 9 a to 9 d of the pipe groups adjacent toeach other in the vertical direction.

Further, in order to prevent the resin material flowing into the gaps 7in the step of forming the sealing members by filling a resin material,which will be described later (see FIGS. 13 and 14), the pipe arrayholding member 9 a of each pipe group 10 is brought into close contactwith the pipe array holding members 9 d of another pipe groups 10immediately above and below the foregoing group. Likewise, the pipearray holding members 9 b, 9 c, and 9 d of each pipe group 10 arebrought into close contact with the pipe array holding members 9 c, 9 b,and 9 a of another pipe groups 10 immediately above and below theforegoing group, respectively. The close contact is achieved by using anadhesive.

Next, the heat exchange module 12 shown in FIGS. 12A to 12C is housed inthe housing 102. Here, the heat exchange module 12 is fixed in a statesuch that portions of the pipe array holding members 9 a to 9 d of eachpipe group 10, which are exposed on surfaces of the heat exchange module12, adhere to inner surfaces of the housing 102 with use of an adhesive.

Next, as shown in FIG. 13, first, the housing 102 in which the heatexchange module 12 is housed is attached to a jig 118. The jig 118 iscomposed of a main body plate 118 a, and a pair of pressing plates 118 band 118 c that sandwich the housing 102 at opening thereof on both thesides thereof. Packings 119 are provided between the pressing plates 118b and 118 c and the housing 102.

Further, the jig 118 is configured rotatably around, as the center, anaxis that passes through the center of the inlet 104 and the center ofthe first outlet 105. On the top face of the housing 102, a mask 120 isattached, so that a resin material is prevented from intruding throughthe inlet 104. The mask 120 is provided with apertures so that theinjection holes 114 and 115 are not closed.

Next, as shown in FIG. 14, an injection pot 121 is attached on the topface of the housing 102. The injection pot 121 includes flow paths 124for guiding a resin material 123 injected into the injection pot 121 tothe injection holes 114 and 115. Here, 122 denotes a lid of theinjection pot. It should be noted that in FIG. 14, the heat exchangemodule 12 is shown as viewed from a side thereof.

Further, as shown in FIG. 14, the injection hole 115 shown in theleft-side part of the drawing is formed so as to communicate withinterstices around the pipes 1 between the opening of the housing on theleft side as viewed in the drawing and the outer-side pipe array holdingmember (9 a or 9 d) of each pipe group 10 on the left side as viewed inthe drawing (hereinafter referred to as “first housing space”). On theother hand, the injection hole 115 shown in the right-side part of thedrawing is formed so as to communicate with interstices around the pipes1 between the opening of the housing on the right side as viewed in thedrawing and the outer-side pipe array holding member (9 d or 9 a) ofeach pipe group 10 on the right side as viewed in the drawing(hereinafter referred to as “second housing space”).

Further, the injection holes 114 are formed so as to communicate withinterstices around the pipes 1 between the two inner-side pipe arrayholding members 9 b and 9 c of each pipe group 10 in the housing 2(hereinafter referred to as “third housing space”). Thus, the resinmaterial 123 in the injection pot 121 is filled exclusively in the firsthousing space, the second housing space, and the third housing space,whereby the gaps 7 (FIGS. 9A to 9C and 10) are formed. Further, thefiling of the resin material is carried out while the jig 118 is beingrotated, as described above. Therefore, with the centrifugal forcecaused by this rotation, the flow path 108 is formed in a cylindricalform as shown in FIG. 10.

Further, if the first and second housing spaces do not have an escapethrough which air goes out, when the filling of the resin materialthrough the injection holes 115 is started, these spaces becomecompletely closed spaces, and hence, the filling of the resin materialbecomes difficult. Therefore, as shown in FIGS. 9A to 9C, air vents 116are provided on the side faces of the housing 102 so that the air ventscommunicate with the first and second housing spaces, respectively. Inthe example shown in FIG. 13, the air vents 116 are connected via pipes125 with air vents 117 that are formed so as to communicate with thethird housing space. Air squeezed out of the first and second housingspaces enters the third housing space, and then, is discharged throughthe inlet 104 or the outlet 105.

It should be noted that the function of the pipes 125 is not limited tothis. Each capacity of the first and second housing spaces is smallerthan the capacity of the third housing space, and the filling of theresin material into the first and second housing spaces ends earlier.Therefore, the pipes 125 also function for supplying excess resinmaterial to the third housing space. In other words, in addition to thefunction of allowing the filing of the resin material to the first andsecond housing spaces to be performed smoothly, the pipes 125 also hasthe function of suppressing the waste of resin material, and thefunction of filling the third housing space with the resin material.

Thus, by injecting the resin material with use of the injection pot 121shown in FIG. 14, the first sealing member 103 a is formed in the firsthousing space, while the second sealing member 103 b is formed in thesecond housing space. Further, in the third housing space, the thirdsealing member 103 c is formed. Still further, since the resin materialfilled in the third housing space is subjected to the centrifugal forcecaused by the rotation of the jig 118, the flow path 108 is formed inthe third housing space. Patent document 1: JP 2005-224301 A

DISCLOSURE OF INVENTION Problem to be Solved by the Invention

However, the above-described method for manufacturing the heat exchangerhas a risk that the pipes 125 (see FIG. 13) could be disengaged due tothe rotation of the jig 118 for the filling of a resin material. In thiscase, the filling of the resin material has to be stopped temporarily,and the already filled resin material could possibly be cured before thefilling operation is restarted. This makes it impossible to complete theproduct.

Still further, in the above-described method for manufacturing the heatexchanger, the resin material filled in the first and second housingspaces also is subjected to the centrifugal force caused by the rotationof the jig 118. As a result, a space in which a resin material is notfilled (air reservoir) could occur in regions of the outer-side pipearray holding members 9 a and 9 b, on the sides of the ends of the pipegroup 10 (see regions A and B shown in FIG. 12A). In this case, areas ofadhesion of the pipe array holding members 9 a, 9 b with the resinmaterial decrease, whereby the air tightness and durability of thesealing members 103 a and 103 b (see FIGS. 9A to 9C) decrease. Stillfurther, it is very difficult, in a post-processing step, to fill aresin material into a space where a resin material has not been filled.

It is an object of the present invention to provide a heat exchanger inwhich the above-described problem is solved and the occurrence of an airreservoir at sealing portions is suppressed, a method for manufacturingthis heat exchanger, and a method for manufacturing a heart-lungmachine.

Means for Solving Problem

In order to achieve the above-described object, a method of the presentinvention for manufacturing a heat exchanger is a method formanufacturing a heat exchanger that includes pipes through which a firstfluid flows, and a housing, wherein the housing has a pair of openingsthat expose ends of the pipes on both sides, an inlet for introducing asecond fluid into the housing, and an outlet provided so as to beopposed to the inlet, the outlet being for discharging the second fluid,and the second fluid comes into contact with surfaces of the pipes. Themethod includes the steps of (a) forming a heat exchange module thatincludes a plurality of pipes arrayed in parallel with one another in atwo-dimensional form, and fixing members that are present in intersticesaround the pipes to hold the array of the plurality of pipes, whereinfour pieces of the fixing members are arranged along a central axisdirection of the pipes with spaces therebetween; (b) providing walls onrespective outer peripheral portions of the fixing members, wherein eachof the walls has a through hole going through in a thickness directionof the wall, and protrudes toward outside of the heat exchange module;(c) arranging flow path members, each of which is arranged between thewalls on the outer-side fixing member positioned closely to an end ofthe tube and on the inner-side fixing member adjacent to the outer-sidefixing member so as to communicate with the through holes provided inthe walls; (d) housing the heat exchange module into the housing, andbringing parts of the outer peripheral portions of the fixing memberswhere the walls are not provided, and the walls, into close contact withinner surfaces of the housing; and (e) while rotating the housing aroundan axis that passes through the centers of the inlet and the outlet,filling a resin material into interstices around the pipes presentbetween one of the openings of the housing and the outer-side fixingmember adjacent thereto, interstices around the pipes present betweenthe other opening of the housing and the outer-side fixing memberadjacent thereto, and interstices around the pipes present between thetwo inner-side fixing members, and further, forming a flow path betweenthe two inner-side fixing members through which the second fluidintroduced through the inlet is guided to the outlet.

Further, in order to achieve the above-described object, a method of thepresent invention for manufacturing a heart-lung machine includes theabove-described method of the present invention for manufacturing a heatexchanger.

Still further, in order to achieve the above-described object, a heatexchanger of the present invention includes a heat exchange module, ahousing that houses the heat exchange module, and sealing members,wherein the heat exchange module includes a plurality of pipes throughwhich a first fluid flows, and fixing members, wherein the plurality ofpipes are arrayed in parallel with one another in a two-dimensionalform, the fixing members are present in interstices around the pipes tohold the array of the plurality of pipes, and four pieces of the fixingmembers are arranged along a central axis direction of the pipes withspaces therebetween, and walls are provided on outer peripheral portionsof the fixing members, each of the walls having a through hole goingthrough in a thickness direction of the wall, and protruding towardoutside of the heat exchange module; the housing has a pair of openingsthat expose ends of the pipes on both sides, an inlet for introducing asecond fluid flowing over surfaces of the plurality of pipes into thehousing, and an outlet disposed so as to be opposed to the inlet, theoutlet being for discharging the second fluid, wherein inner surfaces ofthe housing are brought into close contact with parts of the outerperipheral portions of the fixing members where the walls are notprovided, and with the walls; the sealing members include a firstsealing member, a second sealing member, and a third sealing member,wherein the first sealing member is formed with a resin material filledin interstices around the pipes positioned between one of the openingsof the housing on one side and the outer-side fixing member positionedclosely to ends of the pipes on said side; the second sealing member isformed with a resin material filled in interstices around the pipespositioned between the other one of the openings of the housing on theother side and the outer-side fixing member positioned closely to endsof the pipes on the other side; the third sealing member is formed witha resin material filled in interstices around the pipes present betweenthe two inner-side fixing members; and a flow path through which thesecond fluid introduced through the inlet is guided to the outlet isformed with the third sealing member between the two inner-side fixingmembers.

Effects of the Invention

As described above, in the present invention, when a resin material isfilled, the first and second housing spaces are allowed to communicatewith the third housing space via through holes of two adjacent walls,and flow path members arranged therebetween. The communication of thefirst and second housing spaces with the third housing space isperformed so that a region where air reservoir tends to occur becomes aflow path for a resin material. Therefore, with the present invention,the occurrence of air reservoir can be suppressed, while the degradationof air tightness and durability of sealing members can be suppressed.

BRIEF DESCRIPTION OF DRAWINGS

FIGS. 1A to 1C show a state in which flow path forming members areattached to a heat exchange module. FIGS. 1A, 1B, and 1C are a top view,a front view, and a perspective view, respectively.

FIGS. 2A to 2D show a specific configuration of the flow path formingmember shown in FIGS. 1A to 1C. FIG. 2A is a side view, FIG. 2B is a topview, FIG. 2C is a cross-sectional view taken along a cutting line A-Ain FIG. 2B, and FIG. 2D is a cross-sectional view taken along a cuttingline B-B′ in FIG. 2B.

FIGS. 3A and 3B show a specific configuration of a flow path member.FIG. 3A is a front view, and FIG. 3B is a cross-sectional view.

FIG. 4 is an exploded perspective view of a housing in which a heatexchange module is housed.

FIG. 5 is a perspective view showing a state in which the heat exchangemodule shown in FIGS. 1A to 1C is placed in the housing shown in FIG. 4.

FIG. 6 is a cross-sectional view showing a step for forming a sealingmember.

FIG. 7 is a perspective view showing a heat exchanger according to anembodiment of the present invention.

FIG. 8 is a cross-sectional view showing a heart-lung machinemanufactured by using the method for manufacturing the heat exchangeraccording to the present embodiment.

FIGS. 9A to 9C show a configuration of a conventional heat exchanger.FIGS. 9A, 9B, and 9C are a top view, a side view, and a front view ofthe same, respectively.

FIG. 10 is a partially cut-off perspective view illustrating the insideof a housing of the heat exchanger shown in FIGS. 9A to 9C.

FIGS. 11A to 11C show pipe groups composing a heat exchange module;FIGS. 11A, 11B, and 11C are a top view, a front view, and a perspectiveview, respectively.

FIGS. 12A, 12B, and 12C are a heat exchange module composed of aplurality of pipes; FIGS. 12A to 12C are a top view, a front view, and aperspective view, respectively.

FIG. 13 is a top view illustrating the state in which the housing isattached to a jig so that sealing members are formed.

FIG. 14 is a cross-sectional view showing a step for forming the sealingmembers.

DESCRIPTION OF THE INVENTION

A method of the present invention for manufacturing a heat exchanger isa method for manufacturing a heat exchanger that includes pipes throughwhich a first fluid flows, and a housing, wherein the housing has a pairof openings that expose ends of the pipes on both sides, an inlet forintroducing a second fluid into the housing, and an outlet provided soas to be opposed to the inlet, the outlet being for discharging thesecond fluid, and the second fluid comes into contact with surfaces ofthe pipes. The method includes the steps of: (a) forming a heat exchangemodule that includes a plurality of pipes arrayed in parallel with oneanother in a two-dimensional form, and fixing members that are presentin interstices around the pipes to hold the array of the plurality ofpipes, wherein four pieces of the fixing members are arranged along acentral axis direction of the pipes with spaces therebetween; (b)providing walls on respective outer peripheral portions of the fixingmembers, wherein each of the walls has a through hole going through in athickness direction of the wall, and protrudes toward outside of theheat exchange module; (c) arranging flow path members, each of which isarranged between the walls on the outer-side fixing member positionedclosely to an end of the tube and on the inner-side fixing memberadjacent to the outer-side fixing member so as to communicate with thethrough holes provided in the walls; (d) housing the heat exchangemodule in the housing, and bringing parts of the outer peripheralportions of the fixing members where the walls are not provided, and thewalls, into close contact with inner surfaces of the housing; and (e)while rotating the housing around an axis that passes through thecenters of the inlet and the outlet, filling a resin material intointerstices around the pipes present between one of the openings of thehousing and the outer-side fixing member adjacent thereto, intersticesaround the pipes present between the other opening of the housing andthe outer-side fixing member adjacent thereto, and interstices aroundthe pipes present between the two inner-side fixing members, andfurther, forming a flow path between the two inner-side fixing membersthrough which the second fluid introduced through the inlet is guided tothe outlet.

In the foregoing method of the present invention for manufacturing aheat exchanger, the following is preferable: in the step (a), the heatexchange module is formed by the steps of forming a pipe group thatincludes two or more of the pipes arrayed in a row in parallel with oneanother, and pipe array holding members, each of which is present ingaps between the pipes to hold the array of the two or more pipes, fourpieces of the pipe array holding members being arranged along thecentral axis direction of the pipes with spaces therebetween; andstacking a plurality of the pipe groups, wherein the pipe array holdingmembers of each pipe group are brought into close contact with the pipearray holding members of another pipe groups immediately above and belowthe said group in the central axis direction, so that the fixing membersare formed with the pipe array holding members of the pipe groups, andin the step (b), on at least one of the pipe group positioned in anuppermost layer and the pipe group positioned in a lowermost layer, thewalls are provided on the outer-side pipe array holding memberpositioned closely to the ends of the tubes and the inner-side pipearray holding member adjacent to the outer-side tube array holdingmember in a manner such that the walls are opposed to each other. Thisallows the formation of a heat exchange module to be carried outreadily.

In the foregoing, the following is preferable: in the step (b), on bothof the pipe group positioned in the uppermost layer and the pipe grouppositioned in the lowermost layer, the walls are provided on the twoouter-side pipe array holding members and the two inner-side pipe arrayholding members. In this case, the occurrence of air reservoir can besuppressed further.

In the foregoing method of the present invention for manufacturing aheat exchanger, the following is preferable: the axis that passesthrough the centers of the inlet and the outlet perpendicularly crossesan axis that passes through the centers of the pair of openings, and thethrough holes are provided so as to be positioned on a line that isparallel with the axis that passes through the centers of the pair ofopenings, and that perpendicularly crosses a rotation axis of thehousing. This is because in the foregoing case, a place on the line thatis parallel with the axis that passes through the centers of the pair ofopenings and that perpendicularly crosses the rotation axis of thehousing is the place where air reservoir is most likely to occur.

Further, it is also preferable that the foregoing method of the presentinvention for manufacturing a heat exchanger is further modified so asto include the step of removing the flow path members after the step(e). This makes it possible to seclude the third housing space from thefirst and second housing spaces, thereby isolating these spaces from oneanother. Therefore, it is possible to prevent the first fluid from goingalong the through holes of the walls and the flow path members andintruding into the third housing space, and to prevent the second fluidfrom going along the same and intruding into the first or second housingspace.

Still further, in the above-described method of the present inventionfor manufacturing a heat exchanger, the following is preferable: theflow path members are formed with annular members having elasticity, andin the step (c), the annular members are fitted between the walls in astate of being deformed elastically. In this case, the flow path memberscan be brought into close contact with the walls, wherebyfluid-tightness is ensured in the flow paths formed by the through holesof the two walls and the flow path members.

Still further, in the above-described method of the present inventionfor manufacturing a heat exchanger, the following is preferable: in thestep (b), flow path forming members, each of which has two of the wallsand is formed by connecting the walls in a state in which one wall andthe other wall are opposed to each other, are arranged in a manner suchthat the one wall protrudes from the outer-side fixing member, while theother wall protrudes from the inner-side fixing member adjacent to thesaid outer-side fixing member. This makes the manufacture of a heatexchanger easier.

Still further, in the above-described method of the present inventionfor manufacturing a heat exchanger, the following is preferable: in thestep (e), the resin material is supplied to the interstices around thepipes present between one of the openings of the housing and theouter-side fixing member adjacent thereto, and the interstices aroundthe pipes present between the other opening of the housing and theouter-side fixing member adjacent thereto; and the resin material issupplied further to the interstices around the pipes present between thetwo inner-side fixing members via the through holes of the wallsprovided on the outer-side fixing members, the flow path members, andthe through holes of the walls provided on the inner-side fixing membersadjacent to the outer-side fixing members. This makes it possiblefurther to suppress the occurrence of air reservoir.

Still further, a method of the present invention for manufacturing aheart-lung machine includes the above-described method of the presentinvention for manufacturing a heat exchanger.

A heat exchanger of the present invention includes a heat exchangemodule, a housing that houses the heat exchange module, and sealingmembers, wherein the heat exchange module includes a plurality of pipesthrough which a first fluid flows, and fixing members, wherein theplurality of pipes are arrayed in parallel with one another in atwo-dimensional form, the fixing members are present in intersticesaround the pipes to hold the array of the plurality of pipes, and fourpieces of the fixing members are arranged along a central axis directionof the pipes with spaces therebetween, and walls are provided on outerperipheral portions of the fixing members, each of the walls having athrough hole going through in a thickness direction of the wall, andprotruding toward outside of the heat exchange module, the housing has apair of openings that expose ends of the pipes on both sides, an inletfor introducing a second fluid flowing over surfaces of the plurality ofpipes into the housing, and an outlet disposed so as to be opposed tothe inlet, the outlet being for discharging the second fluid, whereininner surfaces of the housing are brought into close contact with partsof the outer peripheral portions of the fixing members where the wallsare not provided, and with the walls, the sealing members include afirst sealing member, a second sealing member, and a third sealingmember, wherein the first sealing member is formed with a resin materialfilled in interstices around the pipes positioned between one of theopenings of the housing on one side and the outer-side fixing memberpositioned closely to ends of the pipes on said side, the second sealingmember is formed with a resin material filled in interstices around thepipes positioned between the other one of the openings of the housing onthe other side and the outer-side fixing member positioned closely toends of the pipes on the other side, the third sealing member is formedwith a resin material filled in interstices around the pipes presentbetween the two inner-side fixing members, and a flow path through whichthe second fluid introduced through the inlet is guided to the outlet isformed with the third sealing member between the two inner-side fixingmembers.

The heat exchanger of the present invention preferably is configured sothat the walls provided on the outer-side fixing members and the wallsprovided on the inner-side fixing members adjacent to the respectiveouter-side fixing members are formed so that flow path members can bedisposed between the walls so as to communicate with the through holesof the walls. In the case where the heat exchanger of the presentinvention is configured as described above, the heat exchanger can bemanufactured readily by the above-described method of the presentinvention for manufacturing a heat exchanger. Further, in this case, itis preferable that protrusions for positioning the flow path members areformed on a periphery of an opening, on the flow path member side, ofthe through hole of the wall provided on the outer-side fixing member,and on a periphery of an opening, on the flow path member side, of thethrough hole of the wall provided on the inner-side fixing member.

It also is preferable that the above-described heat exchanger of thepresent invention is configured so that the flow path members are formedwith annular members having elasticity, and the walls provided on theouter-side fixing members and the walls provided on the inner-sidefixing members adjacent to the respective outer-side fixing members areformed so that the annular members can be fitted between the walls in astate of elastic deformation. In the case where the above-described heatexchanger of the present invention is manufactured by theabove-described method of the present invention for manufacturing a heatexchanger, the foregoing configuration makes it possible to bring theflow path members into close contact with the walls, wherebyfluid-tightness is ensured in the flow paths formed by the through holesof the two walls and the flow path members.

Still further, the above-described heat exchanger of the presentinvention may be configured as follows: the heat exchange module isformed by stacking a plurality of pipe groups, each of the plurality ofpipe groups includes two or more of the pipes arrayed in a row inparallel with one another, and pipe array holding members, each of whichis present in gaps between the pipes to hold the array of the two ormore pipes. Four pieces of the pipe array holding members are arrangedalong the central axis direction of the pipes with spaces therebetween.The pipe array holding members of each pipe group are brought into closecontact with the pipe array holding members of another pipe groupsimmediately above and below the said group in the central axisdirection, so as to form the fixing members, and on at least one of thepipe group positioned in an uppermost layer and the pipe grouppositioned in a lowermost layer, the walls are provided on theouter-side pipe array holding member positioned closely to ends of thepipes and the inner-side pipe array holding member adjacent to theouter-side pipe array holding member in a manner such that the walls areopposed to each other.

In the foregoing configuration, it is preferable that on both of thepipe group positioned in an uppermost layer and the pipe grouppositioned in a lowermost layer, the walls are provided on the twoouter-side pipe array holding members and the two inner-side pipe arrayholding members. In the case where the above-described heat exchanger ofthe present invention is manufactured by the above-described method ofthe present invention for manufacturing a heat exchanger, the occurrenceof air reservoir can be suppressed further.

Embodiments

The following describes a heat exchanger and a method for manufacturingthe same according to an embodiment of the present invention whilereferring to FIGS. 1 to 7. In the present embodiment, the heat exchangeris for use in medical equipment such as a heart-lung machine used forcontrolling the temperature of blood taken out of a patient.

FIGS. 1A to 1C show a state in which flow path forming members areattached to a heat exchange module. FIGS. 1A, 1B, and 1C are a top view,a front view, and a perspective view, respectively. FIGS. 2A to 2D showa specific configuration of the flow path forming member shown in FIGS.1A to 1C. FIG. 2A is a side view, FIG. 2B is a top view, FIG. 2C is across-sectional view taken along a cutting line A-A′ in FIG. 2B, andFIG. 2D is a cross-sectional view taken along a cutting line B-B′ inFIG. 2B. FIGS. 3A and 3B show a specific configuration of a flow pathmember. FIG. 3A is a front view, and FIG. 3B is a cross-sectional view.

FIG. 4 is an exploded perspective view of a housing in which a heatexchange module is housed. FIG. 5 is a perspective view showing a statein which the heat exchange module shown in FIGS. 1A to 1C is placed inthe housing shown in FIG. 4. FIG. 6 is a cross-sectional view showing astep for forming a sealing member. FIG. 7 is a perspective view showinga heat exchanger according to an embodiment of the present invention.

First, a method for manufacturing a heat exchanger according to thepresent embodiment is described with reference to FIGS. 1 to 6, andthereafter, the heat exchanger according to the present embodiment isdescribed with reference to FIG. 7. It should be noted that in FIGS. 1Ato 1C, and 4 to 7, portions denoted with the same reference numeralsshown in FIGS. 9 to 14 described in the “Background Art” section are thesame as the portions denoted with the foregoing reference numerals inFIGS. 9 to 14.

First, a heat exchange module 12 is formed, which includes a pluralityof pipes 1 arrayed in parallel with one another in a two-dimensionalform, and fixing members, each of which is present in interstices aroundthe pipes to hold the plurality of pipes 1. In the present embodiment 1,the formation of the heat exchange module 12 is similar to that of theexample shown in FIGS. 11 and 12 described in the “Background Art”section; first, a plurality of pipe groups 10 (see FIGS. 11A to 11C) areformed, each of which includes two or more pipes 1 and four pipe arrayholding members 9 a to 9 d; and subsequently, a heat exchange module 12is formed by stacking these pipe groups 10 (see FIGS. 12A to 12C). Inthe present embodiment, cold/hot water for heat exchange flows throughthe insides of the pipes 1.

Further, in the present embodiment, a plurality of pipe array holdingmembers 9 a to 9 d juxtaposed in the vertical direction, in closecontact with each other, compose the above-described fixing members (seeFIGS. 12A to 12C). The fixing members are pierced by the plurality ofpipes 1 arrayed in parallel with one another in a two-dimensional form,thereby holding the two-dimensional array of the plurality of pipes 1.

It should be noted that in the present embodiment, the formation of theheat exchange module 12 is not limited to the above-described example,and the fixing members may be formed integrally by insertion molding atone time. In this case, in the inside of a die for molding, theplurality of pipes 1 are arrayed in parallel with one another in atwo-dimensional form.

Next, as shown in FIGS. 1A to 1C, walls 51 or 52 projecting toward theoutside of the heat exchange module 12 are provided on outer portions ofthe respective fixing members. Each of the walls 51 and 52 has a throughhole that goes through the wall in the thickness direction. In thepresent embodiment, the outer portions of the fixing members are outerportions (outer faces) of the pipe array holding members 9 a to 9 d, andportions (faces) exposed on surfaces of the heat exchange module.Further, in the present embodiment, the walls 51 and 52 are provided onthe uppermost faces of the pipe array holding members 9 a to 9 d of thepipe groups 10 positioned in the uppermost layer, and on the lowermostfaces of the pipe array holding members 9 a to 9 d of the pipe group 10positioned in the lowermost layer.

More specifically, the wall 51 or 52 is mounted by mounting flow pathforming members 50, each of which has the walls 51 and 52, onto the heatexchange module 12. Further specifically, a total of four of the flowpath forming members 50 are mounted, two of which are mounted on thepipe group 10 positioned in the uppermost layer and the other two ofwhich are mounted on the pipe group 10 positioned in the lowermostlayer. It should be noted that the present embodiment is not limited tothis example, and the embodiment may be such that the flow path formingmembers 50 are mounted only on the pipe group 10 positioned in eitherthe uppermost layer or the lowermost layer.

Here, a specific configuration of the flow path forming member 50 isdescribed, with reference to FIGS. 2A to 2D. As shown in FIGS. 2A to 2D,the flow path forming member 50 has the walls 51 and 52. The walls 51and 52 are connected in an opposed state at a certain distance from eachother via a plurality of connecting members 55. The distance between thewalls 51 and 52 is set according to a distance between an outer-sidepipe array holding member and an inner-side pipe array holding memberadjacent thereto, that is, the distance between the pipe array holdingmember 9 a and the pipe array holding member 9 b, and the distancebetween the pipe array holding member 9 c and the pipe array holdingmember 9 d.

Further, in the flow path forming member 50, the wall 51 is providedwith a through hole 53 that goes through the wall in the thicknessdirection (see FIG. 2D). The wall 52 also is provided with a throughhole 54 that goes through the wall in the thickness direction (see FIG.2D). The through holes 53 and 54 are provided so that central axesthereof coincide with each other.

Further, to facilitate the mounting of the flow path forming members 50to the pipe array holding members 9 a to 9 d, a plurality of protrusions61 and a plurality of recesses 60 are formed below the walls 51 and 52,respectively (see FIGS. 2A, 2C, and 2D). More specifically, a pluralityof protrusions 61 are formed so as to be engaged with a plurality ofrecesses 11 of the pipe array holding members 9 a to 9 c exposed onsurfaces of the heat exchange module. The plurality of recesses 60 areformed so as to be engaged with the plurality of pipes 1 composing thepipe group 10 positioned in the uppermost layer or the lowermost layer.Still further, the plurality of protrusions 61 and the plurality ofrecesses 60 are arrayed in a row along the walls 51 and 52. One row ofthe plurality of protrusions 61 and one row of the plurality of recesses60 are formed for each wall.

Therefore, when the flow path forming members 50 shown in FIGS. 2A to 2Dare mounted on the heat exchange module 12, the pipe group 10 positionedin the uppermost layer and the pipe group 10 positioned in the lowermostlayer, the wall 51 or the wall 52 protrudes in the stacking directionfrom each of the pipe array holding members. For example, as shown inFIG. 1C, in the pipe group 10 positioned in the uppermost layer, thewall 52 protrudes from the outer-side pipe array holding member 9 a,while, from the inner-side pipe array holding member 9 b adjacentthereto, the wall 51 protrudes. Still further, from the outer-side pipearray holding member 9 d positioned on the opposite side, the wall 51 ofanother flow path forming member 50 protrudes, while, from theinner-side pipe array holding member 9 c adjacent thereto, the wall 52protrudes. Still further, in the present embodiment, the mounting of theflow path forming members 50 is carried out by the adhesion or fusion ofeach pipe array holding member and each flow path forming member 50, andthey are brought into close contact with each other without interstices.

Further, as shown in FIGS. 2A to 2D, the walls 51 and 52 are formed sothat a flow path member 63 (FIGS. 3A and 3B) that makes the through hole53 and the through hole 54 communicate with each other can be placedbetween the walls 51 and 52. More specifically, on the wall 52 side (theflow path member side) of the wall 51, a pressing part 56 is providedthat protrudes toward the wall 52. On the wall 51 side (the flow pathmember side) of the wall 52, a pressing part 57 is provided thatprotrudes toward the wall 51. Still further, the pressing part 56 isformed so that the through hole 53 pierces the center of the pressingpart 56, while the pressing part 57 is formed so that the through hole54 pierces the center of the pressing part 57.

As shown in FIGS. 2B and 2C, on the periphery of the opening of thethrough hole 53 on the wall 52 side of the wall 51, that is, on theouter portion of the pressing part 56, protrusions 58 for positioningthe flow path member 63 (see FIG. 3 described below) are formed.Likewise, on the periphery of the opening of the through hole 54 on thewall 51 side of the wall 52, that is, on the outer portion of thepressing part 57, protrusions 59 for positioning the flow path member 63are provided.

It should be noted that in the present embodiment, the flow path formingmember 50 is formed by integral molding. However, the present embodimentis not limited to this example, and the flow path forming member 50 maybe configured so that respective parts thereof are formed with separatecomponents.

Subsequently, the flow path member 63 is mounted between the adjacentwalls 51 and 52 of the flow path forming member 50 (see FIG. 5 describedlater). A total of four of the flow path members 63 are mounted, one foreach flow path forming member 50. More specifically, as shown in FIGS.3A and 3B, the flow path member 63 is composed of an annular member(O-ring) formed by an elastic material such as a rubber material or aresin material. The distance between the pressing part 56 and thepressing part 57 is set so as to be smaller than the thickness of theannular member (O-ring) composing the flow path member 63.

For this reason, when the flow path member 63 is placed between thewalls 51 and 52, that is, between the pressing parts 56 and 57, the flowpath member 63 is pressed by the pressing parts 56 and 57, thereby beingsubjected to elastic deformation, into a state of being fitted betweenthe walls 51 and 52 (see FIG. 5 described later). Consequently, thethrough hole 53, an inner circumferential part 64 of the flow pathmember 63, and the through hole 54 forms one flow path (see FIG. 6described later). Still further, since the flow path member 63 isbrought into close contact with the pressing parts 56 and 57 withoutgaps, fluid flowing through this flow path is prevented from leaking.

Next, as shown in FIG. 5, the heat exchange module 12 (see FIGS. 1A to1C) on which the flow path forming member 50 is mounted is housed in thehousing 2 (see FIG. 4). More specifically, in the present embodiment, asshown in FIG. 4, the housing 2 is composed of a housing top part 2 a anda housing bottom part 2 b. Each of the housing top part 2 a and thehousing bottom part 2 b has a channel-shape cross section (anangular-U-shape cross section). When they are bonded in a state in whichthe insides of the channels of these are opposed to each other, anopening 15 a is formed at one end of the housing 2, while an opening 15b is formed at the other end thereof (see FIG. 6). The openings 15 a and15 b are opposed to each other, and through the openings 15 a and 15 b,the ends of the pipes 1 are exposed to the outside of the housing 2.

Further, since blood is guided into the housing 2 in a directioncrossing the direction in which the openings 15 a and 15 b are opposed(hereinafter referred to as an opposing direction of the openings 15 aand 15 b), an inlet 4 for blood is formed on a principal face of thehousing top part 2 a. In the example shown in FIG. 4, the inlet 4 has ashape like a tower protruding from the principal face of the housing toppart 2 a. On a principal face of the housing bottom part 2 b, at aposition opposite to the inlet 4, a circular opening is formed. Thisopening constitutes an outlet 5 for discharging blood. An axis thatpasses through the centers of the inlet 4 and the outlet 5perpendicularly crosses an axis that passes through the centers of apair of openings 15 a and 15 b.

Therefore, in the present embodiment, as shown in FIG. 5, first, theheat exchange module 12 is placed in the housing bottom part 2 b in amanner such that the central axes of the pipes 1 coincide with theopposition direction of the openings 15 a and 15 b, and further, theoutlet 5 faces the pipe group 10 positioned in the lowermost layer.Next, the housing top part 2 a is bonded with the housing bottom part 2b in a manner such that the inlet 4 faces the pipe group 10 positionedin the uppermost layer.

Further, here, in the present embodiment, outer portions of the pipearray holding members 9 a to 9 d of the pipe groups 10, which areexposed on surfaces of the heat exchange module 12 and on which the flowpath forming members 50 are not mounted, are fixed to and brought intocontact with the inner surfaces of the housing 2 with use of anadhesive. Ceiling faces (top faces) of the walls 51 and 52 are fixed toand brought into contact with inner surfaces of the housing 2 with useof an adhesive.

Further, as shown in FIG. 4, on principal faces of the housing upperpart 2 a and the housing lower part 2 b, openings 6 are formed so thatthe flow path forming members 50 are exposed therethrough. Stillfurther, along boundaries between the principal faces and the side facesof the housing upper part 2 a and the housing lower part 2 b, openings13 are formed. Still further, on side faces of the housing upper part 2a and the housing lower part 2 b, notches 14 are formed so as to formopenings on the side faces of the housing 2 when the housing upper part2 a and the housing lower part 2 b are bonded.

Further, the openings 6, the openings 13, and the notches 14 are formedso as to face portions between the outer-side pipe array holding membersand the inner-side pipe array holding members adjacent thereto.Therefore, as shown in FIG. 7 described later, the openings 6, theopenings 13, and the notches 14 function as outlets for dischargingliquid retained in the gaps 7 formed between first and second sealingmembers 3 a, 3 b, and the third sealing member 3 c at the center. Stillfurther, particularly, the openings 6 also function as openings throughwhich the flow path members 63 are taken out after the step for formingthe sealing members is carried out as shown in FIG. 6 described later.

Next, as shown in FIG. 6, while the housing 2 is rotated around an axisthat passes through the center of the inlet 4 and the center of theoutlet 5 of the housing 2, a resin material is filled in the inside ofthe housing 2, whereby the first, second, and third sealing members 3 a,3 b, and 3 c are formed (see FIG. 7). Further, with the third sealingmember 3 c, a flow path 8 (see FIG. 7) for guiding blood introducedthrough the inlet 4 to the outlet 5 is formed. It should be noted thatin FIG. 6, the heat exchange module 12 is shown by a side view.

More specifically, in the present embodiment, the housing 2 is fixed ona rotation table 16 in a state in which the opening 15 a on one side isclosed by a shielding member 18 a, the opening 15 a on the other side isclosed by a shielding member 18 b, and further, the outlet 5 is closedby a shielding member 17. Here, a rotation axis of the rotation table 16and an axis that passes through the center of the inlet 4 and the centerof the outlet 5 of the housing 2 coincide with each other.

Further, an injection pot 19 for retaining a resin material 24 to befilled is placed on a central portion of the top face of the housing 2.The injection pot 19 is provided with supply pipes 20 on its outerportion. This is intended to send out the resin material 24 efficientlyby utilizing centrifugal force. In the example shown in FIG. 6, aY-shaped pipe whose one opening is closed is used as each of the supplypipe 20. The supply pipes 20 are placed at two positions opposite toeach other. The injection pot 19 is configured to close the inlet 4 whenit is placed on the housing, in order to prevent the resin material 24from intruding through the inlet 4.

Further, through holes 23 are provided in the shielding members 18 a and18 b, so as to communicate with the openings 15 a and 15 b of thehousing 2, respectively. Moreover, an injection pipe 22 is attached toeach through hole 23 so that the injection pipe 22 and the through hole23 communicate with each other. In the example shown in FIG. 6, as theinjection pipe 22 also, a Y-shaped pipe whose one opening is closed isused. Each injection pipe 22 is connected with each supply pipe 20 ofthe injection pot 19 via a pipe 21.

Therefore, when the resin material 24 is retained in the injection pot19 and the rotation table 16 is rotated in the foregoing state, theresin material 24 is transferred to the supply pipes 20, the pipes 21,and the injection pipes 22 by the centrifugal force caused by therotation. The resin material 24 is filled in interstices (hereinafterreferred to as “first housing space”) around the pipes 1 present betweenthe opening 15 a of the housing 2 on the left side and the outer-sidepipe array holding member (9 a or 9 d) on the left side, and ininterstices (hereinafter referred to as “second housing space”) aroundthe pipes 1 present between the opening 15 b of the housing 2 on theright side and the outer-side pipe array holding member (9 d or 9 a) onthe right side.

Further, the resin material 24 supplied to the first and second housingspaces is pushed by the resin material 24 transferred later, and a partof the resin material 24 flows through flow paths formed by the throughholes 53 and 54 of the flow path forming members 50 and the flow pathmembers 63. Besides, the resin material 24 having passed through theflow paths enter the interstices around the pipes 1 present between theinner-side pipe array holding members 9 b and 9 c (hereinafter referredto as “third housing space”), whereby the third housing space is filledwith the resin material 24.

Still further, when the filling of the resin material in the first tothird housing spaces is completed and the resin material is cured, theflow path members 63 are removed. With this, the paths that connect thefirst and second housing spaces with the third housing space are closed,whereby these housing spaces are separated. As a result, it is possibleto prevent cold/hot water from going along the through holes 53, 54 andthe flow path members 63 and intruding into the third housing space, andto prevent blood from going along the same and intruding into the firstor second housing space.

Consequently, as shown in FIG. 7, a heat exchanger according to thepresent embodiment is obtained. Like the conventional heat exchangershown in FIGS. 9 and 10 described in the “Background Art” section, theheat exchanger according to the present embodiment also includes a firstsealing member 3 a, a second sealing member 3 b, and a third sealingmember 3 c. It should be noted that the illustration of the housing 2 isomitted in FIG. 7.

The first sealing member 3 a is formed with the resin material 24 filledin the first housing space. The second sealing member 3 b is formed withthe resin material 24 filled in the second housing space. The thirdsealing member 3 c is formed with the resin material 24 filled in thethird housing space.

Further, since the resin material 24 filled in the third housing spaceis subjected to the centrifugal force caused by the rotation, acylindrical space in which the resin material 24 is not filled is formedin the third housing space. The cylindrical space forms a flow path(blood flow path) 8 through which blood introduced through the inlet 4is guided to the outlet 5. Blood passing through the flow path 8 issubjected to heat exchange, via the pipes 1, with cold/hot water passingthrough the pipes 1. Besides, the gaps 7 are formed between the firstsealing member 3 a and the third sealing member 3 c, and between thesecond sealing member 3 b and the third sealing member 3 c, by the pipearray holding members 9 a to 9 d.

In this way, the heat exchanger manufactured by the method formanufacturing the heat exchanger according to the present embodiment hasa configuration identical to that of the conventional heat exchanger.However, in the present embodiment, as shown in FIG. 6, the resinmaterial 24 for forming the third sealing member 3 c (see FIG. 7) istransferred to the third housing space through the flow path formed withthe through holes 53 and 54 of the flow path forming members 50 and theflow path members 63. Thus, a space where conventionally air reservoirtends to occur is used as a flow path for the resin material 24.

Therefore, in the present embodiment, as compared with the conventionalheat exchanger, the occurrence of air reservoir in the first sealingmember 3 a and the second sealing member 3 b is suppressed, and thedegradation of air tightness and reliability of these also issuppressed. In the other words, according to the method formanufacturing the heat exchanger according to the present embodiment,the occurrence of air reservoir is suppressed, whereby the degradationof air tightness and durability of the sealing members of the heatexchanger obtained can be suppressed also.

Further, in the method for manufacturing the heat exchanger according tothe present embodiment, different from the conventional method formanufacturing the heat exchanger shown in FIG. 13, which is described inthe “Background Art” section, it is unnecessary to connect the firsthousing space with the third housing space, and to connect the secondhousing space with the third housing space, via pipes. For this reason,with the method for manufacturing the heat exchanger according to thepresent embodiment, the possibility of suspending the process isreduced, as compared with the conventional method for manufacturing theheat exchanger, whereby the percent of defective products can bereduced.

In the present embodiment, the positions of the through holes 53 and 54formed in the flow path forming members 50 are not limited particularly.However, as shown in FIGS. 1A to 1C, FIGS. 2A to 2D, and FIG. 5, thethrough holes 53 and 54 preferably are positioned on a line that isparallel with the axis passing through the respective centers of theopenings 15 a and 15 b and that perpendicularly crosses the rotationaxis of the housing 2. In other words, the through holes 53 and 54preferably are provided at the centers of the walls 51 and 52. Thereason for this is as follows: in the present embodiment, since the axispassing through the centers of the inlet 4 and the outlet 5, which isthe rotation axis, and the axis passing through the respective centersof the openings 15 a and 15 b cross perpendicularly, air reservoir tendsto occur most likely in a region on the above-described line owing tothe centrifugal force.

Further, in the present embodiment, as shown in FIG. 6, the resinmaterial 24 is injected through the openings 15 a and 15 b of thehousing 2, but the configuration is not limited to this. For example,the configuration may be such that through holes that communicate withthe first housing space and the second housing space are provided onprincipal faces or side faces of the housing 2 so that the resinmaterial 24 is injected through these through holes. Still further, theconfiguration may be such that a through hole that communicates with thethird housing space is provided on a principal face or a side face ofthe housing 2 so that the resin material 24 is filled in the thirdhousing space through both the foregoing through hole and the flow pathsof the flow path forming members 50.

Still further, as shown in FIGS. 1 to 7, in the present embodiment, theflow path forming members 50 and the flow path members 63 are separatecomponents, but the present embodiment is not limited to this example.In other words, in the present embodiment, the flow path forming membermay have a configuration in which the walls 51 and 52 are connected witheach other by a tubular member that communicates with the through holesof the respective walls.

In the present embodiment, examples of the resin material for formingthe sealing members 3 a to 3 c may be thermosetting resins such assilicon resins, polyurethane resins, and epoxy resins. Among these,polyurethane resins and epoxy resins are preferable, in view of theirexcellent adhesion to a material forming the pipes 1 (e.g., a metalmaterial) and a material forming the housing 2 (e.g., a resin materialsuch as a polycarbonate resin).

Further, the method for manufacturing the heat exchanger according tothe present embodiment can be used for manufacturing a heart-lungmachine equipped with the heat exchanger. FIG. 8 is a cross-sectionalview showing a heart-lung machine manufactured by using the method formanufacturing the heat exchanger according to the present embodiment. Itshould be noted that in FIG. 8, portions denoted with the same referencenumerals shown in FIGS. 1 to 7 are the same as the portions denoted withthe foregoing reference numerals in FIGS. 1 to 7.

As shown in FIG. 8, the heart-lung machine is equipped with a heatexchanger 30 and an artificial lung 40, which are housed in a housing31. The housing 31 is provided with a cold/hot water introducing path 32for introducing cold/hot water for heat exchange, a cold/hot waterdischarging path 33 for discharging cold/hot water, a gas introducingpath 34 for introducing oxygen gas, and a gas discharging path 35 fordischarging carbon dioxide, etc., in blood.

The heat exchanger 30 is identical to the heat exchanger shown in FIG.7. In FIG. 7, the heat exchange module 12 is shown in a side view. Inthe heat exchanger 30 shown in FIG. 7, cold/hot water flows through thepipes 1, while blood of a patient flows through the flow path 8. Theartificial lung 40 includes a plurality of hollow fiber membranes 37 andsealing members 38. The sealing members 38 seal the hollow fibermembranes 37 so as to prevent blood from intruding into the gasintroducing path 34 and the gas discharging path 35. The sealing by thesealing members 38 is performed in a manner such that both ends ofhollow fibers forming the hollow fiber membranes 37 are exposed. The gasintroducing path 34 and the gas discharging path 35 communicate witheach other via the hollow fibers forming the hollow fiber membranes 37.

Further, a space in the artificial lung 40 where the sealing members 38are not present forms a blood flow path 39, and the hollow fibermembranes 37 are exposed in the blood flow path 39. Still further, ablood inlet side of the blood flow path 39 communicates with an outletside of the flow path 8 of the heat exchanger 30.

Therefore, blood subjected to heat exchange through the flow path 8flows into the blood flow path 39, where the blood comes into contactwith the hollow fiber membranes 37. Here, oxygen gas flowing through thehollow fiber membranes 37 is captured by the blood. The blood thushaving captured oxygen gas is discharged via a blood outlet 36 providedin the housing 31 to the outside, thereby being returned to the patient.On the other hand, carbon dioxide in the blood is captured by the hollowfiber membranes 37, and is discharged through the gas discharge path 35thereafter.

Thus, in the heart-lung machine shown in FIG. 8, the blood temperatureis controlled by the heat exchanger 30, and blood having been subjectedto the temperature control is subjected to gas exchange by theartificial lung 40. Here, even if the sealing of the heat exchanger 30has a seal leakage so as to cause so as to cause cold/hot water flowingthrough the pipes 1 to flow out, the cold/hot water is retained in thegaps 7, and thereafter is discharged to the outside. Therefore, with theartificial heart-lung machine shown in FIG. 8, the leakage through thesealing can be detected, whereby the contamination of blood withcold/hot water can be suppressed.

INDUSTRIAL APPLICABILITY

As described above, the present invention makes it possible to obtain aheat exchanger having excellent air tightness and reliability ofsealing. The heat exchanger, the method for manufacturing the heatexchanger, and the method for manufacturing the heart-lung machineaccording to the present invention have industrial applicability.

The invention claimed is:
 1. A heat exchanger comprising a heat exchangemodule, a housing that houses the heat exchange module, and sealingmembers, wherein the heat exchange module includes a plurality of pipesthrough which a first fluid flows, and fixing members, wherein theplurality of pipes are arrayed in parallel with one another in atwo-dimensional form and stacked in plural layers, and the fixingmembers are present in interstices around the pipes to hold the array ofthe plurality of pipes, and four pieces of the fixing members arearranged along a central axis direction of the pipes with spacestherebetween, with first and second outer-side fixing members beingpositioned closely to first and second ends of the tube, respectively,on respective outer peripheral portions of the fixing members, flow pathforming members comprising walls are mounted so that the walls protrudetoward outside of the heat exchange module and oppose to each other,each of the walls having a through hole going through in a thicknessdirection of the wall and a pressing member through a center of whichthe through hole pierces, a first flow path member is disposed betweenthe pressing members of the wall provided on the first outer-side fixingmember and the wall provided on a first inner-side fixing memberadjacent to the first outer-side fixing member, so as to communicatewith the through holes of the walls, the first flow path member beingpressed by the pressing members, a second flow path member is disposedbetween the pressing members of the wall provided on the secondouter-side fixing member and the wall provided on a second inner-sidefixing member adjacent to the second outer-side fixing member, so as tocommunicate between the through holes of the walls, the second flow pathmember being pressed by the pressing members, wherein the first andsecond flow path members are not extended to an inside area between thefirst and second inner-side fixing members, thereby being open to theinside area between the first and second inner-side fixing members,while being closed to the area between the adjacent outer-side andinner-side fixing members, the housing has a pair of openings thatexpose ends of the pipes on both sides, an inlet for introducing asecond fluid flowing over surfaces of the plurality of pipes into thehousing, and an outlet disposed so as to be opposed to the inlet, theoutlet being for discharging the second fluid, wherein inner surfaces ofthe housing are brought into close contact with parts of the outerperipheral portions of the fixing members where the walls are notprovided, and with the walls, the sealing members include a firstsealing member, a second sealing member, and a third sealing member,wherein the first sealing member is formed with a resin material filledin interstices around the pipes positioned between one of the openingsof the housing on one side and the outer-side fixing member positionedclosely to ends of the pipes on said side, the second sealing member isformed with a resin material filled in interstices around the pipespositioned between the other one of the openings of the housing on theother side and the outer-side fixing member positioned closely to endsof the pipes on the other side, the third sealing member is formed witha resin material filled in interstices around the pipes present betweenthe first and second inner-side fixing members, thereby leaving gapsbetween the first and third sealing members and between the second andthird sealing members, and a flow path through which the second fluidintroduced through the inlet is guided to the outlet is formed with thethird sealing member between the first and second inner-side fixingmembers, wherein the first and second flow path members each establish aflow path to communicate an outside of the respective outer-side fixingmember with the inside area between the inner-side fixing members in astate before the resin material is filled to form the first to thirdsealing members.
 2. The heat exchanger of claim 1, wherein the flow pathmembers are formed with annular members having elasticity, and the wallsprovided on the first and second outer-side fixing members and the wallsprovided on the inner-side fixing members adjacent to the respectiveouter-side fixing members are formed so that the annular members can befitted between the walls in a state of elastic deformation.
 3. The heatexchanger according to claim 1, wherein protrusions for positioning theflow path members are formed on a periphery of an opening, on the flowpath member side, of the through hole of the wall provided on therespective outer-side fixing member, and on a periphery of an opening,on the flow path member side, of the through hole of the wall providedon the respective inner-side fixing member.
 4. The heat exchangeraccording to claim 1, wherein the heat exchange module is formed bystacking a plurality of pipe groups, each of the plurality of pipegroups includes two or more of the pipes arrayed in a row in parallelwith one another, and pipe array holding members, each of which ispresent in gaps between the pipes to hold the array of the two or morepipes, four pieces of the pipe array holding members being arrangedalong the central axis direction of the pipes with spaces therebetween,the pipe array holding members of each pipe group are brought into closecontact with the pipe array holding members of a pipe group immediatelyabove and a pipe group immediately below the said group in the centralaxis direction, so as to form the fixing members, and on at least one ofthe pipe group positioned in an uppermost layer and the pipe grouppositioned in a lowermost layer, the walls are provided on theouter-side pipe array holding member positioned closely to ends of thepipes and the inner-side pipe array holding member adjacent to theouter-side pipe array holding member in a manner such that the walls areopposed to each other.
 5. The heat exchanger according to claim 4,wherein on both of the pipe groups positioned in an uppermost layer andthe pipe group positioned in a lowermost layer, the walls are providedon the two outer-side pipe array holding members and the two inner-sidepipe array holding members.